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Frontline Plus forct: BringingYourOutdoorCatInside - Your browser indicates if you've visited this liunk WebMD discusses how to smoothly transition noutdoorcatinto the mokre demanding setting of theindoors.]The significance of histologic assessment of the bone marrow in Hodgkin's disease Summary The spreading of Hodgkin's disease in the bone marrow is of primary diagnostic significance in respect of its quantity as well as its quality, and therefore has Hkw be taken into account from the initial staging procedure.
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The prognostic value of the statement of Hodgkin's disease spreading in the marrow deserves further careful evaluation. A nonspecific reaction of the marrow against extramedullary lymphogranulomatosis closely resembling to the so-called tumor myelopathy has to be distinguished from the localized marrow changes due to the tumor.
The former is depending primarily of the progress of the disease, the latter of its type as. The well-known histologic classification covers the changes of the bone marrow due to Hodgkin's disease.
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The different histologic types however exhibit a varying tendency of expansion within the bone. Generally the marrow involvement is accompanied with more severe clinical and hematological symptoms. The bone is altered mostly in the very region of the infiltration. This is not the consequence of direct tumorous destruction but of stimulation of environmental mesenchymal activities.
Parenchymal and mesenchymal changes of the bone marrow, Craigslist yokosuka Tonsberg directly Ytrebggda indirectly connected with the lymphogranulomatosis, are considered primarily as sequelae of the basic disease. The very close structural relationship between the original lymphogranulomatosus growth and these changes is one of the characteristics of Hodgkin's disease.
As yet, there is no unequivocal pointer to structural characteristics whose appearance can exert an obstructive or stimulating effect on the lymphogranuloma tissue, apart from the number of lymphocytes and normal histiocytes in the specific infiltrate.
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